Ecotoxicology

Michael Stoddard Henry

Michael Stoddard Henry

Staff Scientist

Mike Henry joined Mote Marine Laboratory in the summer of 1987 as a staff chemist. He now works in the Ecotoxicology program. This Program assesses what toxic substances are found in the marine environment, where they come from and where the go. Working closely with the other program areas, Mike is involved with extensive field studies backed up by controlled laboratory studies that address chemical changes and metabolic products produced by marine organisms exposed to toxins. A major focus of this program is the analysis of natural biotoxins and pesticides in water, air and marine animals, providing information required to understand how marine life and humans are exposed to biotoxins and in what amounts.

Education

B.S. Chemistry, University of Florida

Publications

R. H. Pierce, M. S. Henry, L. S. Proffitt and A. J. deRosset. 1992. Evaluation of solid sorbents for the recovery of polyether toxins (brevetoxins) in seawater. Bulletin of Environmental Contamination and Toxicology Volume 49, Number 4 / October.

Yousheng Hua ; Wenzhe Lu; Henry M. S. ; Pierce R.H. ; Cole R.B. 1995. On-line high-performance liquid chromatography-electrospray ionization mass spectrometry for the determination of brevetoxins in red tide algae. Analytical chemistry, vol. 67, no11, pp. 1815-1823

Leighfield T.A.; Henry M.S.; Pierce R.H.; Van Dolah F.M.; Zhou J. Receptor binding assay and HPLC analysis of brevetoxins in organisms exposed to a Florida red tide. 1996. Toxicon, Volume 34, Number 3, March, pp. 336-336(1)

Yousheng Hua, Wenzhe Lu, Michael S. Henry, Richard H. Pierce and Richard B. Cole. 1996. On-line liquid chromatography-electrospray ionization mass spectrometry for determination of the brevetoxin profile in natural "red tide" algae blooms. Journal of Chromatography. Volume 750, Issues 1-2, 25 October, Pages 115-125

Kirkpatrick, B., Hautamaki, R.,  Kane, T, Henry, M.  2001. A pilot study to explore the relationship of occupational exposure to Gymnodinium breve(dinophyceae) toxin and pulmonary function. Harmful Algal Blooms. pp. 447-450.

R. H. Pierce, M. S. Henry, P. C. Blum, J. Lyons, Y. S. Cheng, D. Yazzie and Y. Zhou. 2003. Brevetoxin Concentrations in Marine Aerosol: Human Exposure Levels During a Karenia brevis Harmful Algal Bloom 1Mote Marine Laboratory, 1600 Ken Thompson Parkway, Sarasota, FL 34236, USA, 2Lovelace Respiratory Institute, 2425 Ridgecrest Southeast, Albuquerque, NM 87108, USA, Bulletin of Environmental Contamination and Toxicology Volume 70, Number 1 / January.

Lorraine C. Backer, Lora E. Fleming, Alan Rowan, Yung-Sung Cheng, Janet Benson, Richard H. Pierce, Michael S. Henry, Julia Zaias, Judy Bean, Gregory D. Bossart, David Johnson, Raul Quimbo and Daniel G. Baden. 2003. Recreational exposure to aerosolized brevetoxins during Florida red tide events. Harmful Algae, Volume 2, Issue 1, March , Pages 19-28

Richard H. Pierce, Michael S. Henry, Christopher J. Higham, Patricia Blum, Mario R. Sengco and Donald M. Anderson. 2004. Removal of harmful algal cells (Karenia brevis) and toxins from seawater culture by clay flocculation. Harmful Algae, Volume 3, Issue 2, April, Pages 141-148

Yung Sung Cheng, Jacob D. Mcdonald, Dean Kracko, C. Mitch Irvin, Yue Zhou, Richard H. Pierce, Michael S. Henry, Andrea Bourdelaisa, Jerome Naar, and Daniel G. Baden. 2005. Concentration and Particle Size of Airborne Toxic Algae (Brevetoxin) Derived from Ocean Red Tide Events. Environ Sci Technol. May 15; 39(10): 3443-3449

Lora E. Fleming, Barbara Kirkpatrick, Lorraine C. Backer, Judy A. Bean, Adam Wanner, Dana Dalpra, Robert Tamer, Julia Zaias,Yung Sung Cheng, Richard Pierce, Jerome Naar, William Abraham, Richard Clark, Yue Zhou,Michael S. Henry, David Johnson, Gayl Van De Bogart, Gregory D. Bossart, Mark Harrington, and Daniel G. Baden. 2005. Initial Evaluation of the Effects of Aerosolized Florida Red Tide Toxins (Brevetoxins) in Persons with Asthma. Environmental Health Perspectives, VOLUME 113, NUMBER 5, May. 

Lora E. Fleming, Barbara Kirkpatrick, Lorraine C. Backer,Judy A. Bean, Adam Wanner, Dana Dalpra, Robert Tamer, Julia Zaias, Yung Sung Cheng, Richard Pierce, Jerome Naar, William Abraham, Richard Clark, Yue Zhou, Michael S. Henry, David Johnson, Gayl Van De Bogart, Gregory D. Bossart, Mark Harrington, and Daniel G. Baden. 2005.  Initial Evaluation of the Effects of Aerosolized Florida Red Tide Toxins (Brevetoxins) in Persons with Asthma. Environ Health Perspect. May; 113(5): 650-657.

Leanne J. Flewelling, Jerome P. Naar, Jay P. Abbott, Daniel G. Baden, Nélio B. Barros, Gregory D. Bossart, Marie-Yasmine D. Bottein, Daniel G. Hammond, Elsa M. Haubold, Cynthia A. Heil, Michael S. Henry, Henry M. Jacocks, Tod A. Leighfield, Richard H. Pierce, Thomas D. Pitchford, Sentiel A. Rommel, Paula S. Scott, Karen A. Steidinger, Earnest W. Truby, Frances M. Van Dolah, and Jan H. Landsberg. 2005. Red tides and marine mammal mortalities; Unexpected brevetoxin vectors may account for deaths long after or remote from an algal bloom Nature. June 9; 435(7043): 755-756

R.H. Pierce, M.S. Henry, P.C. Blum, S.L. Hamel, B. Kirkpatrick, Y.S. Cheng, Y. Zhou, C.M. Irvin, J. Naar, A. Weidner, L.E. Fleming, L.C. Backerand D.G. Baden 2005. Brevetoxin composition in water and marine aerosol along a Florida beach: Assessing potential human exposure to marine biotoxins. Harmful Algae, Volume 4, Issue 6, November, Pages 965-972

Ann Abraham, Steven M. Plakas, Zhihong Wang, Edward L.E. Jester, Kathleen R. El Said, Hudson R. Granade, Michael S. Henry, Patricia C. Blum, Richard H. Pierce and Robert W. Dickey. 2006. Characterization of polar brevetoxin derivatives isolated from Karenia brevis cultures and natural blooms. Toxicon, Volume 48, Issue 1, July, Pages 104-115

Spencer E. Fire, Deborah Fauquier, Leanne J. Flewelling, Michael Henry, Jerome Naar, Richard Pierce and Randall S. Wells. 2007 Brevetoxin exposure in bottlenose dolphins (Tursiops truncatus) associated with Karenia brevis blooms in Sarasota Bay, Florida. Marine Biology Volume 152, Number 4 / September.

Michael J. Twiner, Marie-Yasmine Bottein Dechraoui, Zhihong Wang, Christina M. Mikulski, Michael S. Henry, Richard H. Pierce and Gregory J. Doucette. Extraction and analysis of lipophilic brevetoxins from the red tide dinoflagellate Karenia brevis. 2007. Analytical Biochemistry, Volume 369, Issue 1, 1 October, Pages 128-135

Jerome P. Naar, Leanne J. Flewelling, Allison Lenzi, Jay P. Abbott, April Granholm, Henry M. Jacocks, Damon Gannon, Michael Henry, Richard Pierce, Daniel G. Baden, Jennifer Wolny and Jan H. Landsberg. 2007. Brevetoxins, like ciguatoxins, are potent ichthyotoxic neurotoxins that accumulate in fish.Toxicon, Volume 50, Issue 5, October, Pages 707-723

Lora E. Fleming, Barbara Kirkpatrick, Lorraine C. Backer, Judy A. Bean, Adam Wanner, Andrew Reich, Julia Zaias, Yung Sung Cheng, Richard Pierce,Michael Henry, Jerome Naar, William M. Abraham and Daniel G. Baden. Aerosolized Red-Tide Toxins (Brevetoxins) and Asthma. 2007.Chest;131;187-194

Spencer E. Fire, Leanne J. Flewelling, Jerome Naar, Michael J. Twiner,Michael S. Henry, Richard H. Pierce, Damon P. Gannon, Zhihong Wang, Leigh Davidson, Randall S. Wells. Prevalence of brevetoxins in prey fish of bottlenose dolphins in Sarasota Bay, Florida. 2008. MARINE ECOLOGY PROGRESS SERIES Vol. 368: 283-294.

Richard Pierce, Michael Henry and Patricia Blum. Brevetoxin abundance and composition during ECOHAB-Florida field monitoring cruises in the Gulf of Mexico. 2008. Continental Shelf Research, Volume 28, Issue 1, January 2008, Pages 45-58

R. H. Pierce and M. S. Henry. Harmful algal toxins of the Florida red tide (Karenia brevis): natural chemical stressors in South Florida coastal ecosystems. 2008. Ecotoxicology; Volume 17, Number 7 / October.

Catherine J. Walsh, Stephanie R. Leggett, Michael S. Henry, Patricia C. Blum, Shannon Osborn and Richard H. Pierce. 2009. Cellular metabolism of brevetoxin (PbTx-2) by a monocyte cell line (U-937). Toxicon, Volume 53, Issue 1, January, Pages 135-145

Yung Sung Cheng, Yue Zhou, Richard H. Pierce, Mike Henry and Daniel G. Baden. 2010. Characterization of Florida red tide aerosol and the temporal profile of aerosol concentration. Toxicon; 55 922-929

Cliff Ross, Raphael Ritson-Williams, Richard Pierce , J. Bradley Bullington ,Michael Henry, Valerie J. Paul. 2010. Effects of the Florida red tide dinoflagellate, Karenia brevis, on oxidative stress and metamorphosis of larvae of the coral Porites astreoides. Harmful Algae 9 173-179

Barbara Kirkpatrick, Richard Pierce, Yung Sung Cheng, Michael S. Henry, Patricia Blum, Shannon Osborn, Kate Nierenberg, Bradley A. Pederson, Lora E. Fleming, Andrew Reich, Jerome Naar, Gary Kirkpatrick, Lorraine C. Backer, Daniel Baden. 2010. Inland transport of aerosolized Florida red tide toxins. Harmful Algae 9 186-189